Australia’s Ben Simmons returned from missing two NBA games with illness and despite his game-high 28 points, Philadelphia were beaten 110-103 by Toronto on Sunday night in Florida.
Simmons, who also had nine rebounds and five assists, scored 13 of his 18 first-half points in the second quarter, and was backed up by a Joel Embiid double-double (25 points, 17 rebounds).
But the Eastern Conference-leading 76ers (20-11) lost for the 16th straight road game against the Raptors.
Fred VanVleet had 23 points and nine assists, Pascal Siakam scored 23 points to go with his seven rebounds and eight assists, and Aussie Aron Baynes chipped in with eight points and five rebounds.
It was the Raptors’ second win in two games against the Sixers this season, after a 100-93 victory on December 29 in Philadelphia.
Toronto finished the first quarter on a 20-2 run to lead 28-24.
Embiid, coming off a 50-point game against Chicago on Friday night, drained a three-pointer to give Philly a three-point lead at the main break.
The 76ers led by as many as 13 points in the third quarter, but their lead was down to one entering the final period.
That’s when Chris Boucher got a hot hand, scoring 11 of his 17 points off the bench to secure Toronto’s (16-15) fourth straight victory.
In New Orleans, Brandon Ingram hit a go-ahead three-pointer with 33.3 seconds left in overtime and the Pelicans after rallied from 24 points down in the third quarter to beat Boston Celtics 120-115.
Ingram finished with 33 points, while Zion Williamson scored 24 of his 28 points after halftime and had 10 rebounds, four assists and a block for the Pels (13-17).
Jayson Tatum had 32 points and nine rebounds for Boston, and Jaylen Brown scored 25 points for the Celtics who drop to 15-15.
Elsewhere, New York Knicks were 103-99 winners at home to Minnesota Timberwolves, and Orlando Magic beat Detroit Pistons 105-96.
Trae Young had 35 points and 15 assists as Atlanta Hawks downed visiting Denver Nuggets 123-115, and Oklahoma City Thunder were 117-101 victors at Cleveland Cavaliers.